PhD Position (m/w/d) - Metaflammation Rheumatologie

Department of Rheumatology and Clinical Immunology (Direktorin: Prof. Dr. Gabriela Riemekasten)

The project is part of the "Metaflammation as a cause and consequence of chronic inflammatory diseases and carcinogenesis" priority program funded by the University of Lübeck (spokesperson: Prof. Dr. Jens Marquardt). The central research topic of the priority program "Metaflammation" is to describe the misprogramming of the immune system by a lifestyle- or environmentally induced chronic, low-active inflammation (metaflammation) in a disease-specific manner and to understand the influence of metaflammation on the respective course of the disease and the response to therapy. The research focus of subproject P06 is on the analysis of correlations between metabolic and immunological factors in chronic inflammatory autoimmune diseases and the development of cardiovascular manifestations. Based on the research group's preliminary work (Müller et al. DOI: 10.1093/eurheartj/ehad666), the research project will address questions relating to the modulation of cellular receptors that are important for cardiovascular manifestations by metabolic and immunological factors.

Start in our team

Are you up for a new challenge? Then join our team and join us as soon as possible as part of your doctoral thesis for a limited period of three years.

What we offer you:

• Placement in pay group E13 TV-L, if the requirements of the collective agreement are met
• Open PhD Position (65%) for 3 years in the Department of Rheumatology & Clinical Immunology
• Access to state-of-art research facilities and laboratory equipment e.g. multiphoton intravital imaging, scRNA-seq, organ-on-a-chip technology, mass spectrometry, cell analyzer, etc.
• Opportunities for attending seminars, lectures, and project meetings as well as the possibility to participate in national and international conferences and workshops form part of our Ph.D. program. 
• Weitere spannende Benefits des UKSH finden Sie hier: Benefits (uksh.de)

What you can expect

• Analysis of changes in cellular metabolism (e.g. using Seahorse technology and molybdenum experiments)
• Conduction of scientific research on intracellular signaling pathways and metabolic analyses
• Use of advanced imaging techniques for immunofluorescence staining
• Presentations at conferences and workshops
• Preparation of reports and scientific publications

What you bring with you:

• Successfully completed university studies in the field of molecular biology, biochemistry, immunology or similar
• Ability to work independently and in a structured manner
• High level of communication and teamwork skills
• Knowledge of biostatistical and bioinformatic analysis is ideal
• Very good written and spoken English skills

We look forward to receiving your application by 16.07.2024, quoting the job advertisement number 24443.